Benefit from testosterone and hydrocortisone on coronary atherogenesis in cockerels on a low protein atherogenic diet.
نویسندگان
چکیده
• During the course of our studies on the role of hormones in atherosclerosis, we have become increasingly aware of the importance of the protein level in the diet upon the action of hormones." In the present study, therefore, the lipid and atherogenic responses to the administration of an anabolic hormone, testosterone propionate, and a catabolic hormone, hydrocortisone (compound F), were analyzed at two different levels of protein in a cholesterol-oil supplemented diet.
منابع مشابه
Effects of Hypothyroidism on Estrogen-Induced Inhibition of Coronary Atherogenesis in Cholesterol-Fed Cockerels
Five series of experiments were accomplished, utilizing a total of 190 birds. The established methods of the department's atherosclerosis research team were followed throughout. One-day old Hy-Line chicks were obtained from a commercial hatchery and reared in a battery brooder on a diet of commercial chick starter mash. At onset of the study, the birds were divided into experimental groups and ...
متن کاملEffects of dietary proteins, methionine and vitamins on plasma lipids and atherogenesis in cholesterol-fed cockerels.
Methionine deficiency in the presence of a high-fat, high-cholesterol diet aggravates atherogenesis in the cockerel. High-protein, high-vitamin supplementation suppresses the atherogenic effect of a cholesterol-fat-containiiig diet. High-protein supplementation alone had a suppressive effect; high-vitamin supplementation had no effect. However, the combined protein and vitamin supplement was th...
متن کاملEstrogen-induced regression of coronary atherosclerosis in cholesterol-fed chicks.
The present study demonstrates that estrogens reverse previously induced coronary atherosclerosis in cholesterol-fed cockerels, despite the continued presence of the atherogenic stimulus in the diet. Aorta atherogenesis remains unaffected. Hypercholesterolemia is moderately enhanced by estrogen administration; total cholesterol-lipid phosphorus (C/P) ratios are depressed to normal levels, conse...
متن کاملAiidrojjen Inhibition of Atherogenesis in Pullets
THE higher incidence of coronary atherosclerosis in young male as compared with young female humans is well established as are similar sex differences in susceptibility in some other species. The administration of female sex hormones to cholesterol-fed cockerels has been reported to have beneficial prophylactic as well as therapeutic effects on coronary atherosclerosis. In one study reported by...
متن کاملFailure off D- and L-Thyroxine to Protect Cholesterol and Oil Fed Cockerels Against Coronary Atherogenesis
• It has been demonstrated that thyroid hormone and its analogues reduce plasma cholesterol levels both in hypoand in euthyroid individuals; and also that D-thyroxine is much less toxic and less calorigenic than L-thyroxine. Katz and Pick reported that thyroid hormone given to chicks on an atherogenic diet, either as desiccated thyroid or thyroxine, suppressed hypercholesterolemia, but the effe...
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عنوان ژورنال:
- Circulation research
دوره 17 6 شماره
صفحات -
تاریخ انتشار 1965